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A key question was whether the virus directly elicited or activated resistance or resistance rested on a pre-existing genetic change (mutation)

By elucidating the essential stress mitigation pathways that facilitate the survival of DTP cells during treatment, we discuss the potential treatment strategies to target DTP cells for durable cure of hematopoietic malignancies

Cell Line: 22Rv1 cells Concentration: 0.1 M, 0.5 M, 1 M, 10 M Incubation Time: 6 hours Result: Significant reduction of downstream phosphorylation of RNA Pol II at Ser2 and Ser7, and diminished phosphorylation at Ser5

doi: 10.1016/j.jdermsci.2010.03.003

Phenotypic and functional heterogeneity of cancer-associated fibroblast within the tumor microenvironment