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359 The inhibition of MELK expression significantly downregulates the expression of the ferroptosis-related genes PTGS2 and SLC39A14 and significantly reduces the expression of the lipid peroxidation marker 4-HNE and the oxidative stress marker MPO, thereby inhibiting macrophage infiltration and M1 polarization, reducing the secretion of proinflammatory factors, and alleviating intestinal tissue damage and intestinal inflammation

Epitalon is a synthetic peptide based on the naturally occurring Epithalamin , a substance originally isolated from the pineal gland

Gene-environment interaction studies As described above, various factors, the dual interplay between genetic susceptibility and environmental exposures, defined here as radiation, chemicals, and additional external factors, have become a critical area of research on the lengthy issue of breast cancer origin

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