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Venous blood samples were collected 0, 0.5-, 1-, 1.5-, 2-, 3-, 4-, 6-, 8-, 12-, and 24-hours after ingestion and were analyzed for plasma and leukocyte vitamin C concentration

IL-15 is required for postexercise induction of the pro-oxidative mediators PPARdelta and SIRT1 in male mice Endocrinology 155 1: 143-55

PMID: 16482209

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Altered mitochondrial function leads to a reduction in energy production and an increase in reactive oxygen species, which negatively impacts all cellular functions such as calcium handling, anaplerosis, proteostasis, apoptosis, and autophagy [27,28,29]