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These findings indicate that the combination of GO-PEI-PEG delivering PD-L1 siRNAs with oral sorafenib can stimulate adaptive immunity and tumor ferroptosis, offering a promising treatment for advanced HCC patients
Nature, 540: 276-279
Dizziness and Pre-Syncope: By supporting the synthesis of norepinephrine via the enzyme dopamine beta-hydroxylase, Vitamin C helps the autonomic nervous system maintain adequate blood flow to the brain, reducing dizzy spells

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68 Cardiac changes include biventricular hypertrophy (RV comprising 67% of heart weight compared with 30% of normal weight), myofiber degeneration, calcification, and mitochondrial damage