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These findings establish innate RNA sensing as an intrinsic driver of hematopoietic stem cell aging and highlight modulation of MDA5-dependent pathways as a potential strategy to mitigate age-related hematopoietic dysfunction

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Su principal funcin es transportar los cidos grasos a las mitocondrias, donde se queman para producir energa

rather, there are studies to suggest that lack of GPx-1 enhances survival to peroxynitrite (136) by mechanisms that are not well understood