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Soliman H, Theret M, Scott W, Hill L, Underhill TM, Hinz B, Rossi FMV

Plaitakis et al., 2017)

10.1111/j.1439-037X.2009.00382.x 53 DolatabadianA.SanavyS

Disruptions in cerebral perfusion, whether due to trauma, ischemia, or hemorrhage, are well-established drivers of acute neuronal injury

Besides eNOS uncoupling, inhibition of the enzyme may also result in a significant drop in vascular NO levels, resulting in endothelial dysfunction and alterations in vascular tone, which may lead to hypertension
