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For example, the Mcl-1/Bax ratio increases following GM-CSF stimulation in neutrophils from individuals of a younger age, whereas this ratio remains unchanged in neutrophils from older individuals [132, 133]

10.1111/cpr.12991 [DOI] [PMC free article] [PubMed] [Google Scholar] Ma C., Xiang J., Huang G., Zhao Y., Wang X., Wu H., et al

A single exposure (A) causes a small decrease (less than 3% of normal), in both blood and cytosolic GSH and Cys concentrations, with levels returning to above 99% of normal for all species within the simulated time-span

doi: 10.1681/ASN.2009040450 83 MarcinkowskaJMielczarekMSroczynskaPSroczynskiJLachowskaJSeniorKet al

ATFS-1, a key regulator of mitochondrial UPR, increases the expression of SKN-1 and the chaperones, such as hsp-6 and hsp-60 , in response to mitochondrial disturbances 64,65