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Description
It is studied for its selective action on lipolytic pathways without activating the IGF-1 receptor
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5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase, an enzyme almost always shortened to NNMT

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Allergy 2007;62:1341-2
By selectively blocking NNMT, 5-Amino-1MQ is investigated for its ability to preserve cellular NAD+ pools, reduce methylation of nicotinamide to inactive 1-methylnicotinamide (1-MNA), and enhance sirtuin activity and energy metabolism
