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For C 55 -P binding, the two sites with the highest predicted affinities (i.e., lowest k off , see Methods) are a pair of equivalent sites at the dimer interface, on each side of the MraY protomers, with k off values of ~1.0 s 1 (Fig

The apobec-1 editing complex is expressed in the intestine and edits a specific cytidine to an uracil in the apo B mRNA in the intestine creating a stop codon that results in the cessation of protein translation and a shorter Apo B (Apo B-48)

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