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Timing and impact of psychiatric, cognitive, and motor abnormalities in Huntington disease

5.2 Oxysterols in neuroinflammation 5.2.1 Oxysterols activate neurons and astrocytes to mediate their cytotoxic and pro-inflammatory effect While several oxysterols have been described to activate pro-inflammatory signaling and cell death pathways in neurons and astrocytes, several studies have proposed that 27-OHC and 24S-OHC are the primary mediators of these effects

K., Dubick, M

Despite the advantages, the application of AI is challenged in many facets, including the black box effect of DL models, bias in the datasets used for the model, and the models ability to be generally applicable to the population and imaging modalities used

To solve this, we must look at advanced delivery methods