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Contemporary researches on hypothermia primarily focuses on its effects at both systemic and organ-specific levels (Bjertnaes et al., 2022)

Ampk promotes macrophage fatty acid oxidative metabolism to mitigate inflammation: Implications for diabetes and cardiovascular disease

GSH participates in neuronal protection and maintaining neurotransmitter balance, while vitamin C supports the synthesis of certain mediators and antioxidant flow in nervous tissue

doi: 10.1021/tx00041a001

This damage triggers the recruitment of fibroblasts and immune cells such as macrophages and neutrophils to injury site