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Across seventeen representative studies, formulations incorporating polyphenols, terpenoids, polyamines, polysaccharides, fatty acids, bioactive peptides, amino acids, vitamins, and minerals produced measurable improvements of approximately 1540% in biomarkers and functional indices associated with ageing (Table 9) [168,169,170]

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This finding suggests that dopaminergic strategies could act on this mechanism and play roles in the antidepressant response, and drugs that modify the inflammasome could also be considered as novel therapeutic agents for depression