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For those patients in the acute phase, pharmacotherapy provides the potential to improve function, reduce deformity, and stabilize scar progression (5)

[98] Rapid weight loss may cause secondary issues such as nutritional deficiencies or muscle loss

3.2 Oxidative stress-related pathway Oxidative stress is a state of imbalance between oxidation and antioxidation, which is considered to be an important factor leading to aging and disease

Trumbo P, Schlicker S, Yates AA, Poos M, Food and Nutrition Board of the Institute of Medicine, The National Academies

Microbiome interventions are promising but need better long term safety and efficacy data
