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Description
These intermediates can then be used in the synthetic route outlined in Scheme 7 to produce the desired Fer-1 analogs with ester bioisosteres that are resistant to esterases (FIG
PMID: 10440166
We next examined enzymes that oxidize GSH to GSSG by performing PCR arrays on panels of glutathione peroxidase enzymes
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In the context of the present invention, pharmaceutical activity encompasses prophylactic and therapeutic activities
