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Most GI symptoms are significantly milder than they were during the 4mg and 8mg escalation phases, even though the absolute dose is higher
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In addition, blood samples were also collected from patients on days 0, 1, 2, 3, 4, 8 and 15 of the first cycle and days 0, 8 and 15 of the second cycle for measurement of TdR, dUrd, Hcy and MMA concentrations