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In a large scale of distinctive targets, always using a triple regimen, it was possible to identify the particular effect of NOS-inhibition (L-NAME), the particular effect of NOS-over-stimulation (L-arginine), and the particular effect of NO-system immobilization (use of both NOS-antagonist and NOS-agonist together)

*Correspondence: Ailing Chen [email protected] Yu [email protected] These authors have contributed equally to this work This article was submitted to Clinical Nutrition, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Anjum et al., 2012a, 2014

However, other studies have reported inhibitory effects on neurogenesis in mice [183, 186]