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[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Katafuchi T, Kondo T, Take S, and Yoshimura M

However, treatment of sepsis based on anti-tumor necrosis factor (TNF)- antibody and interleukin (IL)-1 receptor antagonist did not demonstrate any clinical benefit (2022)

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Clinical studies report occasional mild headaches as the primary adverse event, with research showing no significant increase in cortisol or prolactin levels