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Description
10.1071/PP98083 Funct
Shukla S, Chen ZS, Ambudkar SV
Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload
Importantly, bioenergetic decline in the aged heart predisposes to cardiovascular diseases, including heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation, and contributes to the heightened vulnerability of the elderly to cardiac insults
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