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If left untreated, severe vitamin B12 deficiency can lead to complications such as megaloblastic anemia, nerve damage, and neurological disorders

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[DOI] [PMC free article] [PubMed] [Google Scholar] Chen D

NAD-related biochemical processes

Additional biochemical assays were used to test the ability of compounds to inhibit nicotinamide phosphoribosyl transferase (NAMPT) and NAD + -dependent protein deacetylase sirtuin 1 (SIRT1), two enzymes in the NAD + biosynthesis/salvage pathway
