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Pollution and environmental damage
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In the gut, T cells maintain immune balance, differentiating into proinflammatory (Th1, Th17) or anti-inflammatory [Th2, regulatory T cells (Tregs)] subsets ( 2.1.3 The link between gut microbiome and AD AD, based on emerging research over the past two decades, may be associated with chronic stress, where prolonged exposure to adverse life events (such as MDD and anxiety) increases the risk of developing the disease (Huang et al., 2024)
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