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In untreated models, prolonged traversal times reflect significant coordination difficulties, comparable to the postural instability seen in Parkinsons patients, where such balance issues substantially impact patient safety and quality of life
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In contrast to behaviorally induced sleep delay, these patients cannot fall asleep earlier unless very sleep-deprived
A recent study has provided evidence that HMGB1 is a specific DAMP released by ferroptotic cells in an autophagy-dependent manner ( Figure 3
