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In murine models, fluoxetine, escitalopram, venlafaxine, duloxetine and desipramine showed to alter gut microbiota composition, mainly reducing Ruminococcus, Adlercreutzia and an unclassified Alphaproteobacteria [263]

R., & Lundgren, J
The glucagon receptor component adds a metabolic dimension that previous compounds lacked, increasing energy expenditure while simultaneously reducing appetite through GLP-1 and GIP pathways

Keywords: obesity, glucagon, GLP-1, GIP, dual-agonist therapies, triple agonist therapies Obesity Obesity is a complex, chronic, miscellaneous disease marked by excessive fat accumulation that significantly impacts health with an alarming rise in global prevalence, affecting over 890 million adults by the year 2022

doi: 10.2174/1570159X15666170116143743 40 UbhiKMasliahE
