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Conversely, in patients with impaired brain function with normal ammonia levels, NIRS data were significantly improved in the l-carnitine group than that in the control group

Kastenmller are co-inventors (through Duke University/Helmholtz Zentrum Mnchen) on patents on applications of metabolomics in diseases of the central nervous system and hold equity in Chymia LLC and IP in PsyProtix and Atai that are exploring the potential for therapeutic applications targeting mitochondrial metabolism in treatment-resistant depression

Puerarin Inhibits Fundc1-Mediated Mitochondrial Autophagy and Cse-Induced Apoptosis of Human Bronchial Epithelial Cells by Activating the Pi3k/Akt/Mtor Signaling Pathway

Some RCT evidence exists to support the use of colchicine, potaba, L-carnitine and liposomal superoxide dismutase

Second, the paired pre- and post-intervention design reduces inter-individual variability and strengthens inference regarding diet-associated metabolic changes