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Out of the ten biomarker diagnostic candidates, six are in early development and four in late development, with studies evaluating their diagnostic performance

The remarkable reduction of NAD + concentration and NAD + /NADH ratio in aged rats occurs in parallel with enhanced oxidative stress and diminished antioxidant capacity

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Copper is involved in vascular inflammation as an etiologic factor of atherosclerotic vascular disease, and by chelating copper, TTM may modulate copper-related pathways involved in atherosclerosis and inflammation