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These findings with catalase suggest potential molecular targets that may be modulated by loss of intracellular hydrogen peroxide, although a role for GPx-1 in the regulation of cyclins and cell-cycle progression has not yet been shown

Dong H, Toyoda N, Yoneyama H, Kurachi M, Kasahara T, Kobayashi Y, Inadera H, Hashimoto SI, Matsushima K (2002) Gene expression profile analysis of the mouse liver during bacteria-induced fulminant hepatitis by a cDNA microarray system

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Chronic structural problems like advanced arthritis and complete ligament ruptures show more variable responses