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556 Despite the efficacy of existing drugs, achieving a functional cure remains challenging

Despite these promising findings, some preclinical models have also reported paradoxical pro-tumor effects or significant adverse outcomes, such as exacerbating metastasis and cachexia, under specific conditions, highlighting context-dependent responses [148, 149]

Statistical analysis Sample sizes for single-nucleus transcriptomics and DREADD experiments were determined based on prior experience with similar paradigms 12,13

[4] [5] Background and chronic use [edit] In the United States, medical cannabis research is limited by federal restrictions

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