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10.1182/blood.2020009404 74 ShanX.LiJ.LiuJ.FengB.ZhangT.LiuQ.et al (2023)

Introduction The liver is a major site of metabolism and detoxification of drugs and xenobiotics in the human body ( CYP2E1 ) increases, with an increase in the formation of a highly reactive toxic intermediate metabolite, N-acetyl-p-benzoquinone imine (NAPQI) (Wang et al., 2017)

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