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Baseline bloodwork should include a comprehensive metabolic panel, fasting insulin, fasting glucose, HbA1c, lipid panel, liver enzymes (AST and ALT), IGF-1 levels, thyroid panel, and for men, testosterone levels

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mTORC1 activates the expression of Cxcl9 by up-regulating STAT1 and increasing the binding of STAT1 to the Cxcl9 promoter in osteoblasts [42], suggesting that insulin might promote angiogenesis via Cxcl9