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Relevant studies suggest that high SDF significantly increases the risk of male infertility, worsens outcomes of assisted reproductive technologies (e.g., increased miscarriage rates), and may increase the risk of genetic abnormalities in offspring (96, 97)

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Evidence from clinical studies and systematic analyses indicates that long-term or moderately high doses of supplemental vitamin D can increase the risk of hypercalcemia in a small subset of individuals

doi: 10.3390/ijms25094627 96 SuM.JinR.ZhuJ.PeiJ.WangY.ChaiX.et al