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The NLRP3 inflammasome is a complex consists of a sensor (NLRP3 protein), an adaptor (apoptosis-associated speck-like protein, ASC), and an effector (caspase-1)

10.1016/j.pjnns.2013.04.001 127 JinH.ShenJ.WangB.WangM.ShuB.ChenD

In der Monotherapie (Phase II, Lancet 2021) betrug die Gewichtsreduktion 6,010,8 % ber 26 Wochen
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