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Induction of CAIA and in vivo imaging Nine or ten weeks old female wild-type BALB/c were injected with a 2 mg Arthrogen-CIA-5-Clone monoclonal antibody Cocktail (Chondrex) through intravenous (i.v.)

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Methylthioninium chloride (MTC), also known as methylene blue, and leuco-methylthioninium bis(hydromethanesulfonate) (LMTM), a reduced stable form of methylthioninium (MT) with a greater absorption rate than MTC has, are other compounds whose repositioning for PD treatment has been studied