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The overstimulation of neurons activates microglia, the resident immune cells of the brain, which release proinflammatory cytokines, such as TNF- and IL-1, as well as ROS (Figure 1)

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(PubMed) These findings are intriguing, particularly because aging interventions with multi-year follow-up are relatively rare

The dressing and splint are commonly left on for 10 to 14 days after surgery to keep the wound sterile and keep stress off of the fused joint

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