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The meta-analysis data on L-carnitine showed an average weight reduction of 1.21 to 1.33 kg compared to placebo groups, according to studies published in Clinical Nutrition ESPEN and Obesity Reviews

Individual Variability : Factors such as age, overall health, and the presence of other medical conditions can significantly influence an individuals response to B12 deficiency treatment, as well as the duration of their recovery

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While vitamin B 12 deficiency is not a primary test in newborn screening programs, a study showed that markers C3, C3/C2, and C3/C16 exhibit a negative correlation with maternal levels of vitamin B 12 in the first trimester of pregnancy, and thus may bear diagnostic value (Dayaldasani et al., 2014)