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Realizing that (systemic) inflammation plays an essential role of PD, at least in its maintenance, might pave the way for new therapeutic pathways

Needly and Jones, London: Whittingham and Rowland for Sherwood (1817)

The vitamins synthesized by the GM are important for bacterial metabolism, but there is also evidence that vitamins will enter the organismal vitamin metabolism pathways

Consequently, the skin becomes more resistant to environmental damage

Taking into account all the above-mentioned, monitoring oxidative stress related-parameters during the course of CIPN could be helpful in clinical practice (Areti et al., Figure 2 Diabetic neuropathy Peripheral diabetic neuropathy (PDN) is the most common diabetic complication in patients with diabetes (both type 1 and type 2)