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Theoretically, chronic lipolysis activation could deplete essential lipid stores or disrupt adipose tissue-derived signaling pathways (via adipokines), though this remains speculative

Depending on the severity and the progression of the neuropathy, muscle atrophy also occurs

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Holo-transcobalamin (holoTC), the biologically active form of vitamin B 12 in blood, also has a wide window with indeterminate levels, 36 and the reference values strongly depend on the assay method

This has enabled deeper investigation into molecular mechanisms and peptide-mediated biological processes