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In conditions like pyridoxine-dependent epilepsy or isoniazid toxicity, pyridoxine administration replenishes PLP stores, thereby restoring normal neurotransmitter levels and terminating seizures

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At the time of the switch, a subset of patients expressed concerns about the long-term impact that it would have on their condition management, and in an online survey many stated that they were dissatisfied with the level of care received

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