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If a project is prioritized above the funding line, applicants must submit a complete application within 30 days of the Board-approved prioritization

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Since linear tetrapyrroles, such as bilirubin, play a significant role as antioxidant and anti-inflammatory agents, the reduction of protoheme synthesis by B6 unavailabilty and its further degradation to bilirubin allows further vulnerability to inflammation and oxidative stress

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