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Description
The competitive binding of nicotine to nicotinic cholinergic receptors induces a rapid transient allosteric conformational change to form a selective ionic channel
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Mesas are preparations made by religious specialists following different criteria to please the living forces that make the landscape ( huacas , saxras , etc.) and to which they are offered as food through burning
The tobacco is either kept whole or crumbled and burned as part of the ritual, often accompanied by personal prayers and requests for guidance or protection
These two remained significant after accounting for the confounding factors
