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The Lancet , 398(10317), 2160-2172

Vitamin B12 is also associated with fat and carbohydrate metabolism and protein synthesis

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155,156 While corticosteroids have shown limited efficacy and potential adverse effects in clinical trials, NSAIDs, particularly those with selective cyclooxygenase-2 inhibition, have demonstrated some protective effects in experimental models

It is widely available as an over-the-counter medication, with usual doses ranging from 600 mg to 1,200 mg per day