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At the two-year mark, 77.1% of semaglutide participants maintained at least 5% weight loss versus 34.4% on placebo

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Dr R Venkatakrishnan, consultant cardiologist at Rela Hospital, described GLP-1 analogues as a major addition to cardiovascular risk reduction strategies

Cell culture studies HEK293T cells (CRL-3216, ATCC) were cultured in DMEM (11995073, Life Technologies) supplemented with 10% heat-inactivated FBS (10500064, Life Technologies), 100 IU ml 1 penicillin and 100 g ml 1 streptomycin solution (Pen/Strep, P4333, Sigma Aldrich)

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