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Van Roon-Mom WM, Pepers BA, T Hoen PA et al (2008) Mutant huntingtin activates nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntingtons disease
IGF-1 is the major regulator of growth and controls bone elongation by promoting chondrocyte proliferation and hypertrophy [2,3]
doi: 10.3390/ijms22042058

Future treatment strategies may not be limited to a single approach

Swisher SG , Hofstetter WL Komaki R, Correa AM, Erasmus J, Liao Z, Lee JH, Maru DM, Mehran RJ, Patel S, Phan A, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Ajani JA