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An upregulation of the Nox4 expression with downregulation of the catalase expression and/or activity in diabetes increases the hydrogen peroxide concentration which promotes retinal neovascularization through the VEGF signaling pathway [82]
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Tests for statistical significance were conducted by unpaired t -tests using GraphPad software
Note: Collagen is a slow-burn supplement
Protective effects of Clostridium butyricum in a murine model of dextran sodium sulfate-induced colitis that involve inhibition of the TLR2 signaling pathway and T helper 17 cells
