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While this trial showed trends toward fat loss in the treatment groups, the primary endpoint of statistically significant weight reduction compared to placebo was not consistently achieved across all dose groups, and effect sizes were more modest than hoped

[DOI] [PubMed] [Google Scholar] Krivic A, Majerovic M, Jelic I, Seiwerth S, Sikiric P

Safe B12 Dosing and Monitoring for Older People Establishing appropriate B12 dosing for elderly patients requires consideration of the underlying cause of deficiency, severity of symptoms, and individual patient factors

Jonathan Hommel for guidance in the original study design, and Dr

[DOI] [PubMed] [Google Scholar] 102.Zhao Y., Lai Y., Konijnenberg H., Huerta J.M., Vinagre-Aragon A., Sabin J.A., Hansen J., Petrova D., Sacerdote C., Zamora-Ros R., et al