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Retatrutide cleared Phase 3 last week with 28.3% average weight loss at the high dose, plus a clinically meaningful drop in osteoarthritis pain as a secondary endpoint

The degeneration of dopaminergic neurons affects motor symptoms and non-motor functions

First, this study was limited to preclinical experimental models, including oxidative stress (HO), inflammatory macrophage activation (LPS), and ex vivo human hair follicle culture, which do not completely represent specific disease models of androgenetic alopecia, or telogen effluvium

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Animal ethical approval was obtained from the Ethic Committee of the College of Medicine and Health Sciences, U.A.E