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The molecular mass of TTR was independently confirmed by time-of-flight liquid chromatography-mass spectrometry (LC/MS TOF 6230B, Agilent, Santa Clara, CA, USA)

For example, certain alkyl phospholipid oxidation products in oxidized lowdensity lipoprotein are highaffinity extracellular ligands for peroxisome proliferatoractivated receptor (PPAR) that induce PPARresponsive genes [116]