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Tirzepatide is commonly discussed around GIP and GLP-1 pathway research, while Retatrutide is commonly discussed around GIP, GLP-1 and glucagon pathway research

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Figure 30: Photograph of Professor Sir Stephen Bloom, 2013, credit: Bloom

TRIUMPH Trials: Individual Study Breakdown TRIUMPH-1: General Obesity Population (COMPLETE) Results confirmed May 21, 2026
The majority of patients across all groups those currently on a GLP-1, thinking of it, or who used to take one said "yes." Among those who used to take a GLP-1, 42% said they gained "some" weight back after stopping treatment
