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Unravelling 5-oxoprolinuria (pyroglutamic aciduria) due to bi-allelic OPLAH mutations: 20 new mutations in 14 families

No significant effects were found on the ratio of pro-inflammatory to anti-inflammatory macrophage subpopulations (CD64 + -Ly6C + and CD64 + -Ly6C , respectively) for the cyanidin-rich diet at both time points, suggesting that cyanidin may promote anti-inflammatory effects within the muscle environment (i.e., independent of macrophage phenotype)

For instance, neurons have high energy demands, and mtDNA damage in the CNS contributes to HIV-associated neurocognitive disorders (HAND) through neuronal energy failure and neuroinflammation (9195)