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Oesterreichische Krankenhaus Pharmazie

Glutathione peroxidase 4 (GPX4) as a selenoperoxidase is a key upstream regulator of ferroptosis which plays two simultaneous roles, one in converting reduced GSH to glutathione disulfide (GSSG) and the other is to inhibit ferroptosis by reducing phospholipid hydroperoxides (PLOOHs) to the corresponding alcohols (PLOHs), thereby preventing the accumulation of lipid peroxides (Jiang et al., 2021)

Defeating Alzheimer's disease and other dementias: a priority for European science and society

Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (vcam-1) deficient mice

In brief, lipidomics for each sample were performed by the Vanquish UPLC systems coupled to a Q Exactive HF (QE-HF) mass spectrometer equipped with HESI (Thermo Fisher Scientific, Waltham, MA)