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Description
While both compounds interact with GLP-1 and GIP pathways, Retatrutide differs as a triple agonist involving glucagon receptor activity

Physiol behav 83:699709

p38-TFEB pathways promote microglia activation through inhibiting CMA-Mediated NLRP3 degradation in parkinson's disease
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Griese M et al

Luciferase-based transactivation assays Cells were seeded in 24-well plates at a density of 10 5 cells/well and allowed to reach 6070% confluence and transfected with Lipofectamine 2000 (Invitrogen) following the manufacturers instructions
