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doi: 10.1016/j.bone.2007.11.006

Over 90% of the bodys 5-HT is synthesized in the gut by enterochromaffin cells, which absorb tryptophan from dietary proteins as a substrate for 5-HT synthesis

Combined targeting of AR signaling and glutamine metabolic pathways holds promise as a new strategy to improve CRPC treatment

doi: 10.1007/s11356-021-16056-x

Observation of an Fe 2+ -bound persulfenate intermediate in the active site of CDO that was fully buried, with no room to spare for additional atoms and with the full hydrogen-bonding potential of both the -amino and -carboxylate satisfied, provided a structural explanation for the high specificity of CDO for Cys as its only substrate (Simmons et al